Antimicrobial resistance: antibacterial clinical development pipeline
نویسندگان
چکیده
منابع مشابه
[Linezolid: antibacterial activity, clinical efficacy and resistance].
Linezolid is a synthetic antibiotic, the first available agent in a new class of antibiotic called the oxazolidinones, whose particular mechanism of action consists in inhibiting the initiation of protein synthesis. Its spectrum of in vitro and in vivo activity includes staphylococci, streptococci, enterococci, corynebacteria and some anaerobic bacteria (Peptostreptococcus, Clostridium, and Fus...
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It is almost impossible to imagine veterinary medicine today without the use of antimicrobials. Shortly after their discovery, antimicrobials found their way into the veterinary world. They have brought many benefits for the health and welfare of both animals and people, such as the lessening of pain and suffering, reduction in shedding of (zoonotic) bacteria and the containment of potentially ...
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The dramatic rise in the number and spread of resistant bacterial species continues. This involves not only bacteria that cause infections in the healthcare sector but also those that originate in the community. Antibiotic resistance rates are rising in almost all bacterial species, including those that are the most common bacterial pathogens in people (Escherichia coli and Staphylococcus aureu...
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Surgical site infections (SSIs) determine an increase in hospitalization time and antibiotic therapy costs. The aim of this study was to identify the germs involved in SSIs in patients from the Clinical Emergency County Hospital of Craiova (SCJUC) and to assess their resistance to antimicrobials, with comparisons between surgical wards and the intensive care unit (ICU). The biological samples w...
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Using an Illumina exome sequencing dataset generated from pediatric Acute Myeloid Leukemia patients (AML; type FLT3/ITD+) a comprehensive bioinformatics pipeline was developed to aid in a better clinical understanding of the genetic data associated with the clinical phenotype. The pipeline starts with raw next generation sequencing reads and using both publicly available resources and custom sc...
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ژورنال
عنوان ژورنال: European Journal of Hospital Pharmacy
سال: 2017
ISSN: 2047-9956,2047-9964
DOI: 10.1136/ejhpharm-2017-001423